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This app allows the exploration of cis-regulatory elements (CREs) active in the developing mouse cerebellum.
If you are using this app, please consult and cite our publication:
Sarropoulos, I., Sepp M. et al. Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells. Science (2021)

1. Select a CRE

You can scroll horizontally to explore additional options.

2. Show in genome browser

Your CRE is shown in red. Other robust/non-robust CREs are shown in dark/light blue respectively.
Genomic interactions highlight CRE assignment to target genes in our study (purple/blue: in/out browser view).
Genomic region displayed:

          

Please select a CRE

3. Plot CRE activity

Cell annotation


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This option is only available for shared CREs, with robust activity in both species.
Download plot

Please select a CRE

4. Download data

Warning: Some of these files are large, so downloading might take a while.
RDS files contain SummarizedExperiment objects (1.16) that can be read into R using readRDS().

Name
Size
Description
(2.0 GB)
CRE by cell matrix with associated information about peaks and cells (mouse).
(4.2 GB)
Gene scores by cell matrix (mouse).
(1.1 GB)
chromVar motif scores (deviations and Z-scores) by cell matrix (mouse).
(70 MB)
Summary information for mouse CREs (genomic and evolutionary characterization, activity etc).
(50 MB)
Summary information for mouse cells (annotation, sample, clusters etc).

(350 MB)
CRE by cell matrix (opossum).
(1.3 GB)
Gene scores by cell matrix (opossum).
(15 MB)
Summary information for opossum CREs.
(1 MB)
Summary information for opossum cells (annotation, sample, clusters etc).